A novel p21 attenuator which is structurally related to sorafenib
نویسندگان
چکیده
منابع مشابه
A novel p21 attenuator which is structurally related to sorafenib.
p21 is a member of the cyclin kinase inhibitor family of proteins and plays pivotal roles in cellular proliferation as well as in the regulation of apoptosis, and thus has diverse functions in diseases as varied as cancer and atherosclerosis. In light of its pleiotropic effects and potential clinical relevance, new methods of attenuation of p21 protein levels by selective inhibitors are therefo...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2013
ISSN: 1538-4047,1555-8576
DOI: 10.4161/cbt.23374